VEGFR1 and VEGFR2 involvement in extracellular galectin-1- and galectin-3-induced angiogenesis.
AIM: Accumulating evidence suggests that extracellular galectin-1 and galectin-3 promote angiogenesis.Increased expression of galectin-1 and/or galectin-3 has been reported to be associated with tumour progression.Thus, it is critical to identify their influence on angiogenesis.METHODS: We examined the individual and combined effects of galectin-1